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Target
Prostaglandin D2 receptor
Ligand
BDBM50150975
Substrate
n/a
Meas. Tech.
ChEMBL_305168 (CHEMBL832758)
IC50
2900±n/a nM
Citation
 Torisu, K; Kobayashi, K; Iwahashi, M; Egashira, H; Nakai, Y; Okada, Y; Nanbu, F; Ohuchida, S; Nakai, H; Toda, M Discovery of new chemical leads for prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett 14:4557-62 (2004) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_MOUSE | Prostanoid DP receptor | Ptgdr
Type:
PROTEIN
Mol. Mass.:
40018.63
Organism:
Mus musculus
Description:
ChEMBL_788408
Residue:
357
Sequence:
MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
  
Inhibitor
Name:
BDBM50150975
Synonyms:
CHEMBL183933 | [1-(4-Butoxy-benzoyl)-2,5-dimethyl-1H-indol-3-yl]-acetic acid
Type:
Small organic molecule
Emp. Form.:
C23H25NO4
Mol. Mass.:
379.4489
SMILES:
CCCCOc1ccc(cc1)C(=O)n1c(C)c(CC(O)=O)c2cc(C)ccc12
Structure:
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