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Target
Prostaglandin E2 receptor EP3 subtype
Ligand
BDBM50150977
Substrate
n/a
Meas. Tech.
ChEMBL_302497 (CHEMBL828213)
Ki
>10000±n/a nM
Citation
 Torisu, K; Kobayashi, K; Iwahashi, M; Egashira, H; Nakai, Y; Okada, Y; Nanbu, F; Ohuchida, S; Nakai, H; Toda, M Discovery of new chemical leads for prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett 14:4557-62 (2004) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP3 subtype
Synonyms:
PE2R3_MOUSE | PGE receptor, EP3 isoform alpha | Prostaglandin E2 receptor EP3 isoform alpha | Prostaglandin E3 | Prostanoid EP3 receptor | Ptger3 | Ptgerep3
Type:
G-protein coupled receptor
Mol. Mass.:
40092.50
Organism:
Mus musculus (Mouse)
Description:
n/a
Residue:
365
Sequence:
MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER
  
Inhibitor
Name:
BDBM50150977
Synonyms:
1-(4-Butoxy-benzoyl)-5-methoxy-2-propyl-1H-indole-3-carboxylic acid | CHEMBL186244
Type:
Small organic molecule
Emp. Form.:
C24H27NO5
Mol. Mass.:
409.4749
SMILES:
CCCCOc1ccc(cc1)C(=O)n1c(CCC)c(C(O)=O)c2cc(OC)ccc12
Structure:
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