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Target
Sphingosine 1-phosphate receptor 5
Ligand
BDBM50152539
Substrate
n/a
Meas. Tech.
ChEMBL_304459 (CHEMBL832507)
EC50
77±n/a nM
Citation
 Clemens, JJ; Davis, MD; Lynch, KR; Macdonald, TL Synthesis of benzimidazole based analogues of sphingosine-1-phosphate: discovery of potent, subtype-selective S1P4 receptor agonists. Bioorg Med Chem Lett 14:4903-6 (2004) [PubMed]  Article 
Target
Name:
Sphingosine 1-phosphate receptor 5
Synonyms:
EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41796.42
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
398
Sequence:
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
  
Inhibitor
Name:
BDBM50152539
Synonyms:
CHEMBL183894 | Phosphoric acid mono-[(1R,2R)-2-amino-1-methyl-2-(6-octyl-1H-benzoimidazol-2-yl)-ethyl] ester; TFA
Type:
Small organic molecule
Emp. Form.:
C18H30N3O4P
Mol. Mass.:
383.4223
SMILES:
CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)[C@@H](C)OP(O)(O)=O
Structure:
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