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Target
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Ligand
BDBM50153713
Substrate
n/a
Meas. Tech.
ChEMBL_302829 (CHEMBL838619)
Ki
21±n/a nM
Citation
 Phaosiri, C; Proteau, PJ Substrate analogs for the investigation of deoxyxylulose 5-phosphate reductoisomerase inhibition: synthesis and evaluation. Bioorg Med Chem Lett 14:5309-12 (2004) [PubMed]  Article 
Target
Name:
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Synonyms:
1-deoxyxylulose-5-phosphate reductoisomerase | DXR_SYNY3 | dxr
Type:
PROTEIN
Mol. Mass.:
42517.94
Organism:
Synechocystis sp. (strain PCC 6803)
Description:
ChEMBL_303054
Residue:
394
Sequence:
MVKRISILGSTGSIGTQTLDIVTHHPDAFQVVGLAAGGNVALLAQQVAEFRPEIVAIRQAEKLEDLKAAVAELTDYQPMYVVGEEGVVEVARYGDAESVVTGIVGCAGLLPTMAAIAAGKDIALANKETLIAGAPVVLPLVEKMGVKLLPADSEHSAIFQCLQGVPEGGLRRIILTASGGAFRDLPVERLPFVTVQDALKHPNWSMGQKITIDSATLMNKGLEVIEAHYLFGLDYDHIDIVIHPQSIIHSLIEVQDTSVLAQLGWPDMRLPLLYALSWPERIYTDWEPLDLVKAGSLSFREPDHDKYPCMQLAYGAGRAGGAMPAVLNAANEQAVALFLQEKISFLDIPRLIEKTCDLYVGQNTASPDLETILAADQWARRTVLENSACVATRP
  
Inhibitor
Name:
BDBM50153713
Synonyms:
3-(N-hydroxyformamido)propylphosphonic acid | 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID | CHEMBL203125 | [3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid | fosmidomycin
Type:
Small organic molecule
Emp. Form.:
C4H10NO5P
Mol. Mass.:
183.0997
SMILES:
ON(CCCP(O)(O)=O)C=O
Structure:
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