Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM26995
Substrate
n/a
Meas. Tech.
ChEMBL_302698 (CHEMBL839571)
Ki
1130000±n/a nM
Citation
 Innocenti, A; Firnges, MA; Antel, J; Wurl, M; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions. Bioorg Med Chem Lett 14:5769-73 (2004) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM26995
Synonyms:
CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide | sulfamoylamine
Type:
n/a
Emp. Form.:
H4N2O2S
Mol. Mass.:
96.109
SMILES:
NS(N)(=O)=O
Structure:
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