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Target
M-phase inducer phosphatase 3
Ligand
BDBM50155593
Substrate
n/a
Meas. Tech.
ChEMBL_306187 (CHEMBL830981)
IC50
>80000±n/a nM
Citation
 Contour-Galcéra, MO; Lavergne, O; Brezak, MC; Ducommun, B; Prévost, G Synthesis of small molecule CDC25 phosphatases inhibitors. Bioorg Med Chem Lett 14:5809-12 (2004) [PubMed]  Article 
Target
Name:
M-phase inducer phosphatase 3
Synonyms:
CDC25C | Dual specificity phosphatase Cdc25C | M-phase inducer phosphatase 3 | MPIP3_HUMAN
Type:
Substrate
Mol. Mass.:
53366.11
Organism:
Homo sapiens (Human)
Description:
P30307
Residue:
473
Sequence:
MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANLSILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMKCSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
  
Inhibitor
Name:
BDBM50155593
Synonyms:
2-Methoxy-6-({methyl-[2-(4-nitro-phenyl)-ethyl]-amino}-methyl)-phenol | CHEMBL186560
Type:
Small organic molecule
Emp. Form.:
C17H20N2O4
Mol. Mass.:
316.3517
SMILES:
COc1cccc(CN(C)CCc2ccc(cc2)[N+]([O-])=O)c1O
Structure:
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