Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50177894
Substrate
n/a
Meas. Tech.
ChEMBL_302766 (CHEMBL838830)
Ki
2.1±n/a nM
Citation
 Henriksen, G; Platzer, S; Hauser, A; Willoch, F; Berthele, A; Schwaiger, M; Wester, HJ 18F-labeled sufentanil for PET-imaging of mu-opioid receptors. Bioorg Med Chem Lett 15:1773-7 (2005) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44431.62
Organism:
MOUSE
Description:
OPIATE Mu OPRM1 MOUSE::P42866
Residue:
398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50177894
Synonyms:
2-Fluoro-N-(1-phenethyl-piperidin-4-yl)-N-phenyl-propionamide | CHEMBL197479 | N-[1-[2-phenylethyl]-4-piperidinyl]-N-phenyl-2-[(+/-)-[18F]fluoropropanamide
Type:
Small organic molecule
Emp. Form.:
C22H27FN2O
Mol. Mass.:
354.461
SMILES:
CC(F)C(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: