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Target
Adenosine receptor A3
Ligand
BDBM50152071
Substrate
n/a
Meas. Tech.
ChEMBL_303007 (CHEMBL830246)
Ki
3±n/a nM
Citation
 Elzein, E; Palle, V; Wu, Y; Maa, T; Zeng, D; Zablocki, J 2-Pyrazolyl-N(6)-substituted adenosine derivatives as high affinity and selective adenosine A(3) receptor agonists. J Med Chem 47:4766-73 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50152071
Synonyms:
2-Hydroxymethyl-5-[6-methylamino-2-(4-quinolin-2-yl-pyrazol-1-yl)-purin-9-yl]-tetrahydro-furan-3,4-diol | CHEMBL183940
Type:
Small organic molecule
Emp. Form.:
C23H22N8O4
Mol. Mass.:
474.472
SMILES:
CNc1nc(nc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O)-n1cc(cn1)-c1ccc2ccccc2n1
Structure:
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