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Target
MO15-related protein kinase Pfmrk
Ligand
BDBM50154603
Substrate
n/a
Meas. Tech.
ChEMBL_306159 (CHEMBL832347)
IC50
35800±n/a nM
Citation
 Bhattacharjee, AK; Geyer, JA; Woodard, CL; Kathcart, AK; Nichols, DA; Prigge, ST; Li, Z; Mott, BT; Waters, NC A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors. J Med Chem 47:5418-26 (2004) [PubMed]  Article 
Target
Name:
MO15-related protein kinase Pfmrk
Synonyms:
Protein kinase Pfmrk
Type:
PROTEIN
Mol. Mass.:
37992.30
Organism:
Plasmodium falciparum
Description:
ChEMBL_640752
Residue:
324
Sequence:
MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLLREIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQILNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLNLTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFLLGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAEDAMKHRYFFNDPLPCDISQLPFNDL
  
Inhibitor
Name:
BDBM50154603
Synonyms:
2-{(2-Hydroxy-ethyl)-[5-(4-methoxy-phenyl)-[1,3,4]oxadiazol-2-yl]-amino}-ethanol | CHEMBL189045
Type:
Small organic molecule
Emp. Form.:
C13H17N3O4
Mol. Mass.:
279.2918
SMILES:
COc1ccc(cc1)-c1nnc(o1)N(CCO)CCO
Structure:
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