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Target
Adenosylhomocysteinase
Ligand
BDBM50422678
Substrate
n/a
Meas. Tech.
ChEMBL_302879 (CHEMBL828793)
Ki
670±n/a nM
Citation
 Wang, M; Zhang, J; Andrei, D; Kuczera, K; Borchardt, RT; Wnuk, SF Are L-adenosine and its derivatives substrates for S-adenosyl-L-homocysteine hydrolase? J Med Chem 48:3649-53 (2005) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN
Type:
PROTEIN
Mol. Mass.:
47714.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507791
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
  
Inhibitor
Name:
BDBM50422678
Synonyms:
CHEMBL2364569
Type:
Small organic molecule
Emp. Form.:
C10H12N6O4
Mol. Mass.:
280.2401
SMILES:
Nc1ncnc2n(cnc12)[C@H]1O[C@@H](CN=O)[C@H](O)[C@@H]1O |r|
Structure:
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