Reaction Details Report a problem with these data
Target
Solute carrier family 15 member 1
Ligand
BDBM50169201
Substrate
n/a
Meas. Tech.
ChEMBL_302952 (CHEMBL841787)
Ki
110000±n/a nM
Citation
 Biegel, A; Gebauer, S; Hartrodt, B; Brandsch, M; Neubert, K; Thondorf, I Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1. J Med Chem 48:4410-9 (2005) [PubMed]  Article 
Target
Name:
Solute carrier family 15 member 1
Synonyms:
Intestinal H(+)/peptide cotransporter | Oligopeptide transporter small intestine isoform | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | S15A1_HUMAN | SLC15A1
Type:
PROTEIN
Mol. Mass.:
78818.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1488839
Residue:
708
Sequence:
MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGPMSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
  
Inhibitor
Name:
BDBM50169201
Synonyms:
(S)-2-{(2S,3R)-2-[((S)-2-Amino-4-methyl-pentanoyl)-methyl-amino]-3-hydroxy-butyrylamino}-4-methyl-pentanoic acid | CHEMBL188159
Type:
Small organic molecule
Emp. Form.:
C17H33N3O5
Mol. Mass.:
359.461
SMILES:
CC(C)C[C@H](N)C(=O)N(C)[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(O)=O
Structure:
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