Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50171366
Substrate
n/a
Meas. Tech.
ChEMBL_304269 (CHEMBL829870)
EC50
8300±n/a nM
Citation
 Chordia, MD; Zigler, M; Murphree, LJ; Figler, H; Macdonald, TL; Olsson, RA; Linden, J 6-aryl-8H-indeno[1,2-d]thiazol-2-ylamines: A1 adenosine receptor agonist allosteric enhancers having improved potency. J Med Chem 48:5131-9 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50171366
Synonyms:
6-(2-Nitro-phenyl)-8H-indeno[1,2-d]thiazol-2-yl-ammonium; iodide | CHEMBL193158 | ChEMBL_318083
Type:
Small organic molecule
Emp. Form.:
C16H12N3O2S
Mol. Mass.:
310.35
SMILES:
[NH3+]c1nc-2c(Cc3cc(ccc-23)-c2ccccc2[N+]([O-])=O)s1
Structure:
Search PDB for entries with ligand similarity: