Reaction Details Report a problem with these data
Target
Somatostatin receptor type 2
Ligand
BDBM50370617
Substrate
n/a
Meas. Tech.
ChEMBL_306782 (CHEMBL831537)
IC50
2.2±n/a nM
Citation
 Deshmukh, MV; Voll, G; Kühlewein, A; Mäcke, H; Schmitt, J; Kessler, H; Gemmecker, G NMR studies reveal structural differences between the gallium and yttrium complexes of DOTA-D-Phe1-Tyr3-octreotide. J Med Chem 48:1506-14 (2005) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SSR2_MOUSE | Smstr2 | Somatostatin receptor | Somatostatin receptor 2 | Somatostatin receptor type 2 | Sst2 | Sstr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41234.26
Organism:
MOUSE
Description:
SOMATOSTATIN SST2 SSTR2 MOUSE::P30875
Residue:
369
Sequence:
MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50370617
Synonyms:
CHEMBL1791313 | CHEMBL1791314
Type:
Small organic molecule
Emp. Form.:
C65H92N14O18S2
Mol. Mass.:
1421.639
SMILES:
C[C@H](O)[C@@H](CO)NC(=O)C1CSSC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)CN2CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@H](C)O)C(=O)N1
Structure:
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