Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50009698
Substrate
n/a
Meas. Tech.
ChEMBL_302941 (CHEMBL841776)
Ki
1081±n/a nM
Citation
 Chang, LC; von Frijtag Drabbe Künzel, JK; Mulder-Krieger, T; Spanjersberg, RF; Roerink, SF; van den Hout, G; Beukers, MW; Brussee, J; Ijzerman, AP A series of ligands displaying a remarkable agonistic-antagonistic profile at the adenosine A1 receptor. J Med Chem 48:2045-53 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50009698
Synonyms:
CHEMBL48278 | Cyclopentyl-(9-methyl-9H-purin-6-yl)-amine | N6-cyclopentyl-9-methyladenine
Type:
Small organic molecule
Emp. Form.:
C11H15N5
Mol. Mass.:
217.2703
SMILES:
Cn1cnc2c(NC3CCCC3)ncnc12
Structure:
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