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Target
Beta-1,4-galactosyltransferase 1
Ligand
BDBM50370677
Substrate
n/a
Meas. Tech.
ChEMBL_320957 (CHEMBL885364)
Ki
22300±n/a nM
Citation
 Takaya, K; Nagahori, N; Kurogochi, M; Furuike, T; Miura, N; Monde, K; Lee, YC; Nishimura, S Rational design, synthesis, and characterization of novel inhibitors for human beta1,4-galactosyltransferase. J Med Chem 48:6054-65 (2005) [PubMed]  Article 
Target
Name:
Beta-1,4-galactosyltransferase 1
Synonyms:
B4GALT1 | B4GT1_HUMAN | GGTB2
Type:
PROTEIN
Mol. Mass.:
43930.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_940430
Residue:
398
Sequence:
MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPLQGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVPHTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAIIIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYDYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLTINGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS
  
Inhibitor
Name:
BDBM50370677
Synonyms:
CHEMBL609634
Type:
Small organic molecule
Emp. Form.:
C33H43N3O21P2
Mol. Mass.:
879.6495
SMILES:
Cc1ccc2ccc(COC(=O)COCCOCC(=O)NC[C@@H]3O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]4OC([C@H](O)[C@@H]4O)n4ccc(=O)[nH]c4=O)[C@@H](O)[C@@H](O)[C@H]3O)cc2c1 |r|
Structure:
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