Reaction Details Report a problem with these data
Target
Carbonic anhydrase
Ligand
BDBM10867
Substrate
n/a
Meas. Tech.
ChEMBL_347177 (CHEMBL862664)
Ki
41±n/a nM
Citation
 Nishimori, I; Vullo, D; Minakuchi, T; Morimoto, K; Onishi, S; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. Bioorg Med Chem Lett 16:2182-8 (2006) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
Beta-carbonic anhydrase | CYNT_HELPY | Carbonic anhydrase 1 | cynT | hpβCA
Type:
Protein
Mol. Mass.:
25517.77
Organism:
Helicobacter pylori (strain G27)
Description:
O24855
Residue:
221
Sequence:
MKAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVICNMGNVNPPKTSYKESLSTIASIEYAIAHVGVQNLIICGHSDCGACGSVHLIHDETTKAKTPYIANWIQFLEPVKEELKNHPQFSNHFAKRSWLTERLNARLQLNNLLSYDFIQEKASKNELKIFGWHYIIETGRIYNYNFESHFFEPIGETIKQRKSHENF
  
Inhibitor
Name:
BDBM10867
Synonyms:
4-amino-6-chlorobenzene-1,3-disulfonamide | CHEMBL266240 | aromatic/heteroaromatic sulfonamide 12
Type:
Small organic molecule
Emp. Form.:
C6H8ClN3O4S2
Mol. Mass.:
285.728
SMILES:
Nc1cc(Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O
Structure:
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