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Target
Cannabinoid receptor 1
Ligand
BDBM50072769
Substrate
n/a
Meas. Tech.
ChEMBL_414848 (CHEMBL855029)
Ki
3.9±n/a nM
Citation
 Manera, C; Benetti, V; Castelli, MP; Cavallini, T; Lazzarotti, S; Pibiri, F; Saccomanni, G; Tuccinardi, T; Vannacci, A; Martinelli, A; Ferrarini, PL Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists. J Med Chem 49:5947-57 (2006) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1
Type:
Enzyme
Mol. Mass.:
52842.52
Organism:
Mus musculus (Mouse)
Description:
P47746
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50072769
Synonyms:
(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (2-chloro-ethyl)-amide | (5Z,8Z,11Z,14Z)-N-(2-chloroethyl)icosa-5,8,11,14-tetraenamide | CHEMBL151167 | N-(2-chloroethyl)icosa-5,8,11,14-tetraenamide
Type:
Small organic molecule
Emp. Form.:
C22H36ClNO
Mol. Mass.:
365.98
SMILES:
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCCl
Structure:
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