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Target
Mu-type opioid receptor
Ligand
BDBM50195666
Substrate
n/a
Meas. Tech.
ChEMBL_416468 (CHEMBL907181)
Ki
0.130000±n/a nM
Citation
 Rennison, D; Moynihan, H; Traynor, JR; Lewis, JW; Husbands, SM Structural determinants of opioid activity in derivatives of 14-aminomorphinones: effects of changes to the chain linking of the C14-amino group to the aryl ring. J Med Chem 49:6104-10 (2006) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50195666
Synonyms:
CHEMBL443311 | N-cyclopropylmethyl-14beta-[3'-(4'-chlorophenyl)propylamino]-7,8-dihydronormorphinone
Type:
Small organic molecule
Emp. Form.:
C29H33ClN2O3
Mol. Mass.:
493.037
SMILES:
Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NCCCc1ccc(Cl)cc1
Structure:
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