Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50205700
Substrate
n/a
Meas. Tech.
ChEMBL_428388 (CHEMBL917988)
Ki
4.4±n/a nM
Citation
 Volpini, R; Dal Ben, D; Lambertucci, C; Taffi, S; Vittori, S; Klotz, KN; Cristalli, G N6-methoxy-2-alkynyladenosine derivatives as highly potent and selective ligands at the human A3 adenosine receptor. J Med Chem 50:1222-30 (2007) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50205700
Synonyms:
2-[(4-fluorophenyl)ethynyl]-N6-methoxyadenosine | CHEMBL223739
Type:
Small organic molecule
Emp. Form.:
C19H18FN5O5
Mol. Mass.:
415.3751
SMILES:
CONc1nc(nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)C#Cc1ccc(F)cc1
Structure:
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