Reaction Details Report a problem with these data
Target
Dehydrogenase/reductase SDR family member 9
Ligand
BDBM17638
Substrate
n/a
Meas. Tech.
ChEMBL_443070 (CHEMBL892201)
IC50
14000±n/a nM
Citation
 Gebhardt, P; Dornberger, K; Gollmick, FA; Gräfe, U; Härtl, A; Görls, H; Schlegel, B; Hertweck, C Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill). Bioorg Med Chem Lett 17:2558-60 (2007) [PubMed]  Article 
Target
Name:
Dehydrogenase/reductase SDR family member 9
Synonyms:
DHRS9 | DHRS9_HUMAN | RDH15 | SDR9C4
Type:
PROTEIN
Mol. Mass.:
35234.21
Organism:
Homo sapiens (Human)
Description:
ChEMBL_443070
Residue:
319
Sequence:
MLFWVLGLLILCGFLWTRKGKLKIEDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNLADPVKVIEKKLAIWEQLSPDIKQQYGEGYIEKSLDKLKGNKSYVNMDLSPVVECMDHALTSLFPKTHYAAGKDAKIFWIPLSHMPAALQDFLLLKQKAELANPKAV
  
Inhibitor
Name:
BDBM17638
Synonyms:
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid | CHEMBL6 | Indocin | Indomethacin | US11478464, Compound Indomethacin | US11786535, Compound Indomethacin | US9271961, Indomethacin | indometacin
Type:
Small organic molecule
Emp. Form.:
C19H16ClNO4
Mol. Mass.:
357.788
SMILES:
COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1
Structure:
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