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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50219748
Substrate
n/a
Meas. Tech.
ChEMBL_445893 (CHEMBL896183)
Ki
138±n/a nM
Citation
 Ferorelli, S; Abate, C; Colabufo, NA; Niso, M; Inglese, C; Berardi, F; Perrone, R Design and evaluation of naphthol- and carbazole-containing fluorescent sigma ligands as potential probes for receptor binding studies. J Med Chem 50:4648-55 (2007) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50219748
Synonyms:
3,3-dimethyl-1-[5-(9H-carbazol-9-yl)pentyl]piperidine hydrochloride | CHEMBL538091
Type:
Small organic molecule
Emp. Form.:
C24H32N2
Mol. Mass.:
348.5243
SMILES:
CC1(C)CCCN(CCCCCn2c3ccccc3c3ccccc23)C1
Structure:
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