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Target
Deoxynucleoside kinase
Ligand
BDBM50206508
Substrate
n/a
Meas. Tech.
ChEMBL_454747 (CHEMBL886770)
IC50
419000±n/a nM
Citation
 Ciliberti, N; Manfredini, S; Angusti, A; Durini, E; Solaroli, N; Vertuani, S; Buzzoni, L; Bonache, MC; Ben-Shalom, E; Karlsson, A; Saada, A; Balzarini, J Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity. Bioorg Med Chem 15:3065-81 (2007) [PubMed]  Article 
Target
Name:
Deoxynucleoside kinase
Synonyms:
DNK_DROME | Deoxyribonucleoside kinase | Dm-dNK | Multispecific deoxynucleoside kinase | dnk
Type:
PROTEIN
Mol. Mass.:
29092.93
Organism:
Drosophila melanogaster
Description:
ChEMBL_627484
Residue:
250
Sequence:
MAEAASCARKGTKYAEGTQPFTVLIEGNIGSGKTTYLNHFEKYKNDICLLTEPVEKWRNVNGVNLLELMYKDPKKWAMPFQSYVTLTMLQSHTAPTNKKLKIMERSIFSARYCFVENMRRNGSLEQGMYNTLEEWYKFIEESIHVQADLIIYLRTSPEVAYERIRQRARSEESCVPLKYLQELHELHEDWLIHQRRPQSCKVLVLDADLNLENIGTEYQRSESSIFDAISSNQQPSPVLVSPSKRQRVAR
  
Inhibitor
Name:
BDBM50206508
Synonyms:
1-(2'-O-phenylacetyl-beta-D-arabinofuranosyl)-5(E)-(2-bromovinyl)uracil | CHEMBL241407
Type:
Small organic molecule
Emp. Form.:
C19H19BrN2O7
Mol. Mass.:
467.267
SMILES:
OC[C@H]1O[C@H]([C@@H](OC(=O)Cc2ccccc2)[C@@H]1O)n1cc(C=CBr)c(=O)[nH]c1=O |w:22.24|
Structure:
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