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Target
Bcl2-associated agonist of cell death
Ligand
BDBM50371612
Substrate
n/a
Meas. Tech.
ChEMBL_463796 (CHEMBL947936)
Ki
1320±n/a nM
Citation
 Tang, G; Nikolovska-Coleska, Z; Qiu, S; Yang, CY; Guo, J; Wang, S Acylpyrogallols as inhibitors of antiapoptotic Bcl-2 proteins. J Med Chem 51:717-20 (2008) [PubMed]  Article 
Target
Name:
Bcl2-associated agonist of cell death
Synonyms:
BAD | BAD_HUMAN | BBC6 | BCL2L8 | Bcl-2-binding component 6 | Bcl-2-like protein 8 | Bcl-XL/Bcl-2-associated death promoter | Bcl2 antagonist of cell death | Bcl2-L-8 | Bcl2-antagonist of cell death (BAD)
Type:
PROTEIN
Mol. Mass.:
18393.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_478760
Residue:
168
Sequence:
MFQIPEFEPSEQEDSSSAERGLGPSPAGDGPSGSGKHHRQAPGLLWDASHQQEQPTSSSHHGGAGAVEIRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFVDSFKKGLPRPKSAGTATQMRQSSSWTRVFQSWWDRNLGRGSSAPSQ
  
Inhibitor
Name:
BDBM50371612
Synonyms:
CHEMBL259034
Type:
Small organic molecule
Emp. Form.:
C30H20O6
Mol. Mass.:
476.4762
SMILES:
Oc1c(O)c(cc(C(=O)c2cccc3ccccc23)c1O)C(=O)c1ccc(Oc2ccccc2)cc1
Structure:
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