Reaction Details Report a problem with these data
Target
ADP-ribosylation factor 1
Ligand
BDBM50373058
Substrate
n/a
Meas. Tech.
ChEMBL_466424 (CHEMBL936308)
Kd
620±n/a nM
Citation
 Zhang, Q; Major, MB; Takanashi, S; Camp, ND; Nishiya, N; Peters, EC; Ginsberg, MH; Jian, X; Randazzo, PA; Schultz, PG; Moon, RT; Ding, S Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Proc Natl Acad Sci U S A 104:7444-8 (2007) [PubMed]  Article 
Target
Name:
ADP-ribosylation factor 1
Synonyms:
ARF1 | ARF1_HUMAN
Type:
PROTEIN
Mol. Mass.:
20697.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_466424
Residue:
181
Sequence:
MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK
  
Inhibitor
Name:
BDBM50373058
Synonyms:
CHEMBL259181
Type:
Small organic molecule
Emp. Form.:
C36H33N5O2
Mol. Mass.:
567.6795
SMILES:
OC[C@H](Cc1ccccc1)Nc1nc(Oc2ccc3CCCc3c2)nc2n(Cc3ccc(cc3)-c3ccccc3)cnc12
Structure:
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