Reaction Details Report a problem with these data
Target
Sortase family protein
Ligand
BDBM50201782
Substrate
n/a
Meas. Tech.
ChEMBL_474184 (CHEMBL939309)
Ki
15700±n/a nM
Citation
 Maresso, AW; Wu, R; Kern, JW; Zhang, R; Janik, D; Missiakas, DM; Duban, ME; Joachimiak, A; Schneewind, O Activation of inhibitors by sortase triggers irreversible modification of the active site. J Biol Chem 282:23129-39 (2007) [PubMed]  Article 
Target
Name:
Sortase family protein
Synonyms:
Sortase | Sortase A (SrtA)
Type:
Enzyme
Mol. Mass.:
23546.15
Organism:
Staphylococcus aureus
Description:
n/a
Residue:
206
Sequence:
MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQYDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVGVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK
  
Inhibitor
Name:
BDBM50201782
Synonyms:
1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride | CHEMBL264166 | CHEMBL536752
Type:
Small organic molecule
Emp. Form.:
C11H13Cl2NO
Mol. Mass.:
246.133
SMILES:
CN(C)CCC(=O)c1ccc(Cl)c(Cl)c1
Structure:
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