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Target
Mu-type opioid receptor
Ligand
BDBM50261457
Substrate
n/a
Meas. Tech.
ChEMBL_531190 (CHEMBL974076)
IC50
1.21±n/a nM
Citation
 Nemoto, T; Fujii, H; Narita, M; Miyoshi, K; Nakamura, A; Suzuki, T; Nagase, H Syntheses of 4,6'-epoxymorphinan derivatives and their pharmacologies. Bioorg Med Chem 16:4304-12 (2008) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44431.62
Organism:
MOUSE
Description:
OPIATE Mu OPRM1 MOUSE::P42866
Residue:
398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50261457
Synonyms:
17-(Cyclopropylmethyl)-4,6alpha-epoxymethanomorphinan-3,14beta-diol | CHEMBL467788
Type:
Small organic molecule
Emp. Form.:
C21H27NO3
Mol. Mass.:
341.444
SMILES:
Oc1ccc2C[C@@H]3N(CC4CC4)CC[C@]45C[C@H](CC[C@]34O)COc1c25 |r,TLB:8:7:4.24.5:19|
Structure:
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