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Target
Translocator protein
Ligand
BDBM50045877
Substrate
n/a
Meas. Tech.
ChEMBL_556775 (CHEMBL961473)
Kd
4±n/a nM
Citation
 Yu, W; Wang, E; Voll, RJ; Miller, AH; Goodman, MM Synthesis, fluorine-18 radiolabeling, and in vitro characterization of 1-iodophenyl-N-methyl-N-fluoroalkyl-3-isoquinoline carboxamide derivatives as potential PET radioligands for imaging peripheral benzodiazepine receptor. Bioorg Med Chem 16:6145-55 (2008) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50045877
Synonyms:
2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylacetamide | 2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dihexyl-acetamide | CHEMBL63154 | [N,N-di-n-hexyl-2-(4-fluorophenyl) indole-3-acetamide]
Type:
Small organic molecule
Emp. Form.:
C28H37FN2O
Mol. Mass.:
436.6046
SMILES:
CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: