Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 6
Ligand
BDBM50377930
Substrate
n/a
Meas. Tech.
ChEMBL_508179 (CHEMBL1008237)
Ki
328000±n/a nM
Citation
 Kaler, G; Truong, DM; Khandelwal, A; Nagle, M; Eraly, SA; Swaan, PW; Nigam, SK Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem 282:23841-53 (2007) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 6
Synonyms:
Nkt | Oat1 | S22A6_MOUSE | Slc22a6
Type:
PROTEIN
Mol. Mass.:
60032.49
Organism:
Mus musculus
Description:
ChEMBL_508179
Residue:
545
Sequence:
MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPAHHCRPPANANLSKDGGLEAWLPLDKQGRPESCLRFPFPHNGTEANGTGVTEPCLDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLFMVGVLLGAMMFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCIFRLLSGMSLASIAINCMTLNMEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLAVSVPFFVAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLQTSLQKELTLNKGQASAMELLRCPTLRRLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQLASLLLAGICILVNGIIPRGHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTAEFYPSIPLFIFGAVPVAASAVTALLPETLGQPLPDTVQDLKSRSRGKQKQQQLEQQKQMIPLQVSTQEKNGL
  
Inhibitor
Name:
BDBM50377930
Synonyms:
Benzylpenicillin Sodium | PENICILLIN G SODIUM
Type:
Small organic molecule
Emp. Form.:
C16H17N2O4S
Mol. Mass.:
333.383
SMILES:
CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C([O-])=O |r|
Structure:
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