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Target
Carbonic anhydrase
Ligand
BDBM10875
Substrate
n/a
Meas. Tech.
ChEMBL_515851 (CHEMBL993110)
Ki
565±n/a nM
Citation
 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates. Bioorg Med Chem 17:1158-63 (2009) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
CAN_YEAST | NCE103 | NCE3
Type:
PROTEIN
Mol. Mass.:
24861.97
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_1507033
Residue:
221
Sequence:
MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK
  
Inhibitor
Name:
BDBM10875
Synonyms:
5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide | CHEMBL360356 | Chlorzolamide, CHL | JMC522226 Compound 19 | JMC523116 Compound 19 | aromatic/heteroaromatic sulfonamide 20
Type:
Small organic molecule
Emp. Form.:
C8H6ClN3O2S2
Mol. Mass.:
275.735
SMILES:
NS(=O)(=O)c1nnc(s1)-c1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: