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Target
Cation-dependent mannose-6-phosphate receptor
Ligand
BDBM50275807
Substrate
n/a
Meas. Tech.
ChEMBL_492874 (CHEMBL942205)
IC50
23000±n/a nM
Citation
 Jeanjean, A; Gary-Bobo, M; Nirdé, P; Leiris, S; Garcia, M; Morère, A Synthesis of new sulfonate and phosphonate derivatives for cation-independent mannose 6-phosphate receptor targeting. Bioorg Med Chem Lett 18:6240-3 (2008) [PubMed]  Article 
Target
Name:
Cation-dependent mannose-6-phosphate receptor
Synonyms:
M6PR | MPR46 | MPRD | MPRD_HUMAN
Type:
PROTEIN
Mol. Mass.:
30989.41
Organism:
Homo sapiens (Human)
Description:
ChEMBL_492874
Residue:
277
Sequence:
MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSFESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM
  
Inhibitor
Name:
BDBM50275807
Synonyms:
mannose 6-phosphate
Type:
Small organic molecule
Emp. Form.:
C6H12O9P
Mol. Mass.:
259.1284
SMILES:
O[C@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O |r|
Structure:
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