Reaction Details Report a problem with these data
Target
Cation-dependent mannose-6-phosphate receptor
Ligand
BDBM50275808
Substrate
n/a
Meas. Tech.
ChEMBL_492874 (CHEMBL942205)
IC50
22000±n/a nM
Citation
Jeanjean, A; Gary-Bobo, M; Nirdé, P; Leiris, S; Garcia, M; Morère, A Synthesis of new sulfonate and phosphonate derivatives for cation-independent mannose 6-phosphate receptor targeting. Bioorg Med Chem Lett 18:6240-3 (2008) [PubMed] Article
More Info.:
Target
Name:
Cation-dependent mannose-6-phosphate receptor
Synonyms:
M6PR | MPR46 | MPRD | MPRD_HUMAN
Type:
PROTEIN
Mol. Mass.:
30989.41
Organism:
Homo sapiens (Human)
Description:
ChEMBL_492874
Residue:
277
Sequence:
MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSFESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM