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Target
P2Y purinoceptor 14
Ligand
BDBM50303333
Substrate
n/a
Meas. Tech.
ChEMBL_595741 (CHEMBL1045264)
EC50
11±n/a nM
Citation
 Das, A; Ko, H; Burianek, LE; Barrett, MO; Harden, TK; Jacobson, KA Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups. J Med Chem 53:471-80 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50303333
Synonyms:
Diphosphoric Acid 1-beta-(3-Butynyl)Ester 2-(2-Thiouridine-5'-yl)ester, bis-Triethylammonium Salt
Type:
Small organic molecule
Emp. Form.:
C13H16N2O11P2S
Mol. Mass.:
470.287
SMILES:
O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OCCC#C)n1ccc(=O)[nH]c1=S |r|
Structure:
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