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Target
P2Y purinoceptor 14
Ligand
BDBM50303337
Substrate
n/a
Meas. Tech.
ChEMBL_595741 (CHEMBL1045264)
EC50
1900±n/a nM
Citation
 Das, A; Ko, H; Burianek, LE; Barrett, MO; Harden, TK; Jacobson, KA Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups. J Med Chem 53:471-80 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50303337
Synonyms:
Diphosphoric Acid 1-beta-(4-Methoxyphenyl)Ester 2-(Uridine-5'-yl)ester,di ammonium Salt
Type:
Small organic molecule
Emp. Form.:
C16H18N2O13P2
Mol. Mass.:
508.2683
SMILES:
COc1ccc(OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)cc1 |r|
Structure:
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