Reaction Details Report a problem with these data
Target
P2Y purinoceptor 14
Ligand
BDBM50209663
Substrate
n/a
Meas. Tech.
ChEMBL_595741 (CHEMBL1045264)
EC50
11±n/a nM
Citation
 Das, A; Ko, H; Burianek, LE; Barrett, MO; Harden, TK; Jacobson, KA Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups. J Med Chem 53:471-80 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
P2Y14_HUMAN | P2RY14 | GPR105 | KIAA0001 | Purinergic receptor P2Y14 | Insulin Receptor-Related Protein (INSRR)
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Human
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50209663
Synonyms:
MRS-2670 | diphosphoric acid 1-alpha-D-glucopyranosyl ester 2-((4'-thio)uridin-5''-yl) ester | CHEMBL374384
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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