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Target
D(1A) dopamine receptor
Ligand
BDBM50304394
Substrate
n/a
Meas. Tech.
ChEMBL_603130 (CHEMBL1038852)
Ki
2116±n/a nM
Citation
 Schulze, M; Müller, FK; Mason, JM; Görls, H; Lehmann, J; Enzensperger, C Dibenzazecine scaffold rebuilding--is the flexibility always essential for high dopamine receptor affinities? Bioorg Med Chem 17:6898-907 (2009) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50304394
Synonyms:
3-methoxy-5,8,9,13b-tetrahydro-6H-isoquino-[1,2-a]isoquinoline | 3-methoxy-6,8,9,13b-tetrahydro-5H-isoquinolino[1,2-a]isoquinoline | CHEMBL593395
Type:
Small organic molecule
Emp. Form.:
C18H19NO
Mol. Mass.:
265.3496
SMILES:
COc1ccc2C3N(CCc4ccccc34)CCc2c1
Structure:
Search PDB for entries with ligand similarity: