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Target
D(3) dopamine receptor
Ligand
BDBM50304397
Substrate
n/a
Meas. Tech.
ChEMBL_603132 (CHEMBL1038854)
Ki
251±n/a nM
Citation
 Schulze, M; Müller, FK; Mason, JM; Görls, H; Lehmann, J; Enzensperger, C Dibenzazecine scaffold rebuilding--is the flexibility always essential for high dopamine receptor affinities? Bioorg Med Chem 17:6898-907 (2009) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50304397
Synonyms:
3-Methoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline | CHEMBL596448
Type:
Small organic molecule
Emp. Form.:
C18H19NO
Mol. Mass.:
265.3496
SMILES:
COc1ccc2C3Cc4ccccc4CN3CCc2c1
Structure:
Search PDB for entries with ligand similarity: