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Target
D(1B) dopamine receptor
Ligand
BDBM50304404
Substrate
n/a
Meas. Tech.
ChEMBL_603134 (CHEMBL1038856)
Ki
1812±n/a nM
Citation
 Schulze, M; Müller, FK; Mason, JM; Görls, H; Lehmann, J; Enzensperger, C Dibenzazecine scaffold rebuilding--is the flexibility always essential for high dopamine receptor affinities? Bioorg Med Chem 17:6898-907 (2009) [PubMed]  Article 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM50304404
Synonyms:
10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2,7}.0^{16,20}]henicosa-1(14),2(7),3,5,15,20-hexaene | CHEMBL610449
Type:
Small organic molecule
Emp. Form.:
C19H21NO2
Mol. Mass.:
295.3755
SMILES:
CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1
Structure:
Search PDB for entries with ligand similarity: