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Target
Neuraminidase
Ligand
BDBM50320769
Substrate
n/a
Meas. Tech.
ChEMBL_639158 (CHEMBL1167419)
IC50
6500±n/a nM
Citation
 Wen, WH; Wang, SY; Tsai, KC; Cheng, YS; Yang, AS; Fang, JM; Wong, CH Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses. Bioorg Med Chem 18:4074-84 (2010) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I33A0
Type:
PROTEIN
Mol. Mass.:
49687.56
Organism:
Influenza A virus
Description:
ChEMBL_1347422
Residue:
453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWDPNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETIWTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
  
Inhibitor
Name:
BDBM50320769
Synonyms:
5-Acetamido-2,6-anhydro-4-{N-[3-(4-methylpiperazinocarbonyl)propyl]guanidino}-3,4,5-trideoxy-D-glycero-Dgalacto-non-2-enonic acid | CHEMBL1164463
Type:
Small organic molecule
Emp. Form.:
C21H36N6O8
Mol. Mass.:
500.5459
SMILES:
CN1CCN(CC1)C(=O)CCCN([C@H]1C=C(O[C@@H]([C@H](O)[C@H](O)CO)[C@@H]1NC(C)=O)C(O)=O)C(N)=N |r,c:15|
Structure:
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