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Target
Interleukin-5
Ligand
BDBM50320923
Substrate
n/a
Meas. Tech.
ChEMBL_638038 (CHEMBL1166941)
IC50
6100±n/a nM
Citation
 Thanigaimalai, P; Yang, HM; Sharma, VK; Kim, Y; Jung, SH The scope of thallium nitrate oxidative cyclization of chalcones; synthesis and evaluation of isoflavone and aurone analogs for their inhibitory activity against interleukin-5. Bioorg Med Chem 18:4441-5 (2010) [PubMed]  Article 
Target
Name:
Interleukin-5
Synonyms:
IL5_MOUSE | Il-5 | Il5
Type:
PROTEIN
Mol. Mass.:
15414.97
Organism:
Mus musculus
Description:
ChEMBL_1464308
Residue:
133
Sequence:
MRRMLLHLSVLTLSCVWATAMEIPMSTVVKETLTQLSAHRALLTSNETMRLPVPTHKNHQLCIGEIFQGLDILKNQTVRGGTVEMLFQNLSLIKKYIDRQKEKCGEERRRTRQFLDYLQEFLGVMSTEWAMEG
  
Inhibitor
Name:
BDBM50320923
Synonyms:
5-(Cyclohexylmethoxy)-3-(3,4,5-trimethoxyphenyl)-4Hchromen-4-one | CHEMBL1163759
Type:
Small organic molecule
Emp. Form.:
C25H28O6
Mol. Mass.:
424.4862
SMILES:
COc1ccc(c(OC)c1OC)-c1coc2cccc(OCC3CCCCC3)c2c1=O
Structure:
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