Reaction Details Report a problem with these data
Target
Interleukin-5
Ligand
BDBM50320927
Substrate
n/a
Meas. Tech.
ChEMBL_638038 (CHEMBL1166941)
IC50
>30000±n/a nM
Citation
 Thanigaimalai, P; Yang, HM; Sharma, VK; Kim, Y; Jung, SH The scope of thallium nitrate oxidative cyclization of chalcones; synthesis and evaluation of isoflavone and aurone analogs for their inhibitory activity against interleukin-5. Bioorg Med Chem 18:4441-5 (2010) [PubMed]  Article 
Target
Name:
Interleukin-5
Synonyms:
IL5_MOUSE | Il-5 | Il5
Type:
PROTEIN
Mol. Mass.:
15414.97
Organism:
Mus musculus
Description:
ChEMBL_1464308
Residue:
133
Sequence:
MRRMLLHLSVLTLSCVWATAMEIPMSTVVKETLTQLSAHRALLTSNETMRLPVPTHKNHQLCIGEIFQGLDILKNQTVRGGTVEMLFQNLSLIKKYIDRQKEKCGEERRRTRQFLDYLQEFLGVMSTEWAMEG
  
Inhibitor
Name:
BDBM50320927
Synonyms:
(Z)-2-(4-Chlorobenzylidene)-4-(cyclohexylmethoxy)benzofuran-3(2H)-one | CHEMBL1164395
Type:
Small organic molecule
Emp. Form.:
C22H21ClO3
Mol. Mass.:
368.853
SMILES:
Clc1ccc(\C=C2/Oc3cccc(OCC4CCCCC4)c3C2=O)cc1
Structure:
Search PDB for entries with ligand similarity: