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Target
MO15-related protein kinase Pfmrk
Ligand
BDBM50321438
Substrate
n/a
Meas. Tech.
ChEMBL_640752 (CHEMBL1175693)
IC50
600±n/a nM
Citation
 Caridha, D; Kathcart, AK; Jirage, D; Waters, NC Activity of substituted thiophene sulfonamides against malarial and mammalian cyclin dependent protein kinases. Bioorg Med Chem Lett 20:3863-7 (2010) [PubMed]  Article 
Target
Name:
MO15-related protein kinase Pfmrk
Synonyms:
Protein kinase Pfmrk
Type:
PROTEIN
Mol. Mass.:
37992.30
Organism:
Plasmodium falciparum
Description:
ChEMBL_640752
Residue:
324
Sequence:
MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLLREIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQILNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLNLTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFLLGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAEDAMKHRYFFNDPLPCDISQLPFNDL
  
Inhibitor
Name:
BDBM50321438
Synonyms:
2-(3,4-dichlorophenyl)-2-(2-hydroxy-2-phenylethylamino)acetonitrile | CHEMBL1169826
Type:
Small organic molecule
Emp. Form.:
C16H14Cl2N2O
Mol. Mass.:
321.201
SMILES:
OC(CNC(C#N)c1ccc(Cl)c(Cl)c1)c1ccccc1
Structure:
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