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Target
MO15-related protein kinase Pfmrk
Ligand
BDBM50321445
Substrate
n/a
Meas. Tech.
ChEMBL_640752 (CHEMBL1175693)
IC50
16500±n/a nM
Citation
 Caridha, D; Kathcart, AK; Jirage, D; Waters, NC Activity of substituted thiophene sulfonamides against malarial and mammalian cyclin dependent protein kinases. Bioorg Med Chem Lett 20:3863-7 (2010) [PubMed]  Article 
Target
Name:
MO15-related protein kinase Pfmrk
Synonyms:
Protein kinase Pfmrk
Type:
PROTEIN
Mol. Mass.:
37992.30
Organism:
Plasmodium falciparum
Description:
ChEMBL_640752
Residue:
324
Sequence:
MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLLREIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQILNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLNLTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFLLGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAEDAMKHRYFFNDPLPCDISQLPFNDL
  
Inhibitor
Name:
BDBM50321445
Synonyms:
4-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide | CHEMBL1170011
Type:
Small organic molecule
Emp. Form.:
C14H9F6NO2S
Mol. Mass.:
369.282
SMILES:
FC(F)(F)c1ccc(NS(=O)(=O)c2ccc(cc2)C(F)(F)F)cc1
Structure:
Search PDB for entries with ligand similarity: