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Target
MO15-related protein kinase Pfmrk
Ligand
BDBM50321461
Substrate
n/a
Meas. Tech.
ChEMBL_640752 (CHEMBL1175693)
IC50
600±n/a nM
Citation
 Caridha, D; Kathcart, AK; Jirage, D; Waters, NC Activity of substituted thiophene sulfonamides against malarial and mammalian cyclin dependent protein kinases. Bioorg Med Chem Lett 20:3863-7 (2010) [PubMed]  Article 
Target
Name:
MO15-related protein kinase Pfmrk
Synonyms:
Protein kinase Pfmrk
Type:
PROTEIN
Mol. Mass.:
37992.30
Organism:
Plasmodium falciparum
Description:
ChEMBL_640752
Residue:
324
Sequence:
MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLLREIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQILNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLNLTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFLLGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAEDAMKHRYFFNDPLPCDISQLPFNDL
  
Inhibitor
Name:
BDBM50321461
Synonyms:
2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-phenylacetamide | CHEMBL1171238
Type:
Small organic molecule
Emp. Form.:
C12H8BrCl2NO3S2
Mol. Mass.:
429.137
SMILES:
Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1
Structure:
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