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Target
Transcriptional activator protein LuxR
Ligand
BDBM50097224
Substrate
n/a
Meas. Tech.
ChEMBL_643998 (CHEMBL1211897)
IC50
56000±n/a nM
Citation
 Soulère, L; Sabbah, M; Fontaine, F; Queneau, Y; Doutheau, A LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones. Bioorg Med Chem Lett 20:4355-8 (2010) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXR_ALIFS | luxR
Type:
PROTEIN
Mol. Mass.:
28563.86
Organism:
Vibrio fischeri
Description:
ChEMBL_831639
Residue:
250
Sequence:
MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILDNYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLITGFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSNNDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILTGAIDCPYFKN
  
Inhibitor
Name:
BDBM50097224
Synonyms:
1-Methyl-4-thioxanthen-9-ylidene-piperidine | 1-methyl-4-(9H-thioxanthen-9-ylidene)piperidine | CHEMBL152408 | Pimethixene
Type:
Small organic molecule
Emp. Form.:
C19H19NS
Mol. Mass.:
293.426
SMILES:
[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1\c2ccccc2-[#16]-c2ccccc-12
Structure:
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