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Target
Transcriptional activator protein LuxR
Ligand
BDBM61401
Substrate
n/a
Meas. Tech.
ChEMBL_643998 (CHEMBL1211897)
IC50
91000±n/a nM
Citation
 Soulère, L; Sabbah, M; Fontaine, F; Queneau, Y; Doutheau, A LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones. Bioorg Med Chem Lett 20:4355-8 (2010) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXR_ALIFS | luxR
Type:
PROTEIN
Mol. Mass.:
28563.86
Organism:
Vibrio fischeri
Description:
ChEMBL_831639
Residue:
250
Sequence:
MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILDNYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLITGFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSNNDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILTGAIDCPYFKN
  
Inhibitor
Name:
BDBM61401
Synonyms:
3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydrochloride | 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine;hydrochloride | 3,3-diphenylpropyl(1-phenylethyl)amine;hydrochloride | CHEMBL254832 | FENDILINE HYDROCHLORIDE | MLS000069570 | SMR000058827 | cid_5702162
Type:
Small organic molecule
Emp. Form.:
C23H25N
Mol. Mass.:
315.4513
SMILES:
CC(NCCC(c1ccccc1)c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: