Reaction Details Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM50325030
Substrate
n/a
Meas. Tech.
ChEMBL_651607 (CHEMBL1227990)
IC50
>1000±n/a nM
Citation
 Di Cianni, A; Carotenuto, A; Brancaccio, D; Novellino, E; Reubi, JC; Beetschen, K; Papini, AM; Ginanneschi, M Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors. J Med Chem 53:6188-97 (2010) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50325030
Synonyms:
(2S,5R,8S,11S,14S,19S,Z)-5-((1H-indol-2-yl)methyl)-19-((R)-2-amino-3-phenylpropanamido)-8-(4-aminobutyl)-2-benzyl-N-((2R,3R)-1,3-dihydroxybutan-2-yl)-11-(4-hydroxybenzyl)-3,6,9,12,20-pentaoxo-1,4,7,10,13-pentaazacycloicos-16-ene-14-carboxamide | CHEMBL1223231
Type:
Small organic molecule
Emp. Form.:
C56H70N10O10
Mol. Mass.:
1043.216
SMILES:
C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C\C=C/C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1 |r,c:11|
Structure:
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