Reaction Details Report a problem with these data
Target
Somatostatin receptor type 5
Ligand
BDBM50325027
Substrate
n/a
Meas. Tech.
ChEMBL_651608 (CHEMBL1227991)
IC50
12.3±n/a nM
Citation
 Di Cianni, A; Carotenuto, A; Brancaccio, D; Novellino, E; Reubi, JC; Beetschen, K; Papini, AM; Ginanneschi, M Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors. J Med Chem 53:6188-97 (2010) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 5
Synonyms:
SOMATOSTATIN SST5 | SS-5-R | SS5-R | SS5R | SSR5_HUMAN | SSTR5 | Somatostatin receptor type 5 (SSTR5)
Type:
Enzyme
Mol. Mass.:
39218.02
Organism:
Homo sapiens (Human)
Description:
P35346
Residue:
364
Sequence:
MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL
  
Inhibitor
Name:
BDBM50325027
Synonyms:
4-(((3S,6S,9R,12S,15S,20S,Z)-9-((1H-indol-2-yl)methyl)-15-((R)-2-amino-3-phenylpropanamido)-6-(4-aminobutyl)-12-benzyl-20-((2R,3R)-1,3-dihydroxybutan-2-ylcarbamoyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacycloicos-17-en-3-yl)methyl)phenyl benzoate | CHEMBL1223228
Type:
Small organic molecule
Emp. Form.:
C63H74N10O11
Mol. Mass.:
1147.3221
SMILES:
C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C\C=C/C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(OC(=O)c3ccccc3)cc2)C(=O)N1 |r,c:11|
Structure:
Search PDB for entries with ligand similarity: