Reaction Details Report a problem with these data
Target
Somatostatin receptor type 1
Ligand
BDBM50325028
Substrate
n/a
Meas. Tech.
ChEMBL_651604 (CHEMBL1227987)
IC50
>1000±n/a nM
Citation
 Di Cianni, A; Carotenuto, A; Brancaccio, D; Novellino, E; Reubi, JC; Beetschen, K; Papini, AM; Ginanneschi, M Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors. J Med Chem 53:6188-97 (2010) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1)
Type:
Enzyme
Mol. Mass.:
42692.81
Organism:
Homo sapiens (Human)
Description:
P30872
Residue:
391
Sequence:
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
  
Inhibitor
Name:
BDBM50325028
Synonyms:
(2S,5R,8S,11S,14S,19S,Z)-5-((1H-indol-2-yl)methyl)-19-((R)-2-amino-3-phenylpropanamido)-8-(4-aminobutyl)-N-((2R,3R)-1,3-dihydroxybutan-2-yl)-11-((R)-1-hydroxyethyl)-2-(naphthalen-1-ylmethyl)-3,6,9,12,20-pentaoxo-1,4,7,10,13-pentaazacycloicos-16-ene-14-carboxamide | CHEMBL1223229
Type:
Small organic molecule
Emp. Form.:
C55H70N10O10
Mol. Mass.:
1031.2053
SMILES:
C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C\C=C/C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccc3ccccc23)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 |r,c:11|
Structure:
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