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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50327221
Substrate
n/a
Meas. Tech.
ChEMBL_664237 (CHEMBL1261744)
IC50
86000±n/a nM
Citation
 Khattab, SN; Hassan, SY; Bekhit, AA; El Massry, AM; Langer, V; Amer, A Synthesis of new series of quinoxaline based MAO-inhibitors and docking studies. Eur J Med Chem 45:4479-89 (2010) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50327221
Synonyms:
4-Benzoyl-1-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[4,3-a]quinoxaline | CHEMBL1258955
Type:
Small organic molecule
Emp. Form.:
C24H18N4O3
Mol. Mass.:
410.4247
SMILES:
COc1ccc(cc1OC)-c1nnc2c(nc3ccccc3n12)C(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: