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Target
Vitamin D3 receptor
Ligand
BDBM50329719
Substrate
n/a
Meas. Tech.
ChEMBL_674300 (CHEMBL1274500)
EC50
22000±n/a nM
Citation
 Maruyama, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M Novel selective anti-androgens with a diphenylpentane skeleton. Bioorg Med Chem Lett 20:6661-6 (2010) [PubMed]  Article 
Target
Name:
Vitamin D3 receptor
Synonyms:
1,25-dihydroxyvitamin D3 receptor | NR1I1 | Nuclear receptor subfamily 1 group I member 1 | Retinoic acid receptor RXR-alpha/Vitamin D3 receptor | VDR | VDR_HUMAN
Type:
Protein
Mol. Mass.:
48288.72
Organism:
Homo sapiens (Human)
Description:
P11473
Residue:
427
Sequence:
MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS
  
Inhibitor
Name:
BDBM50329719
Synonyms:
CHEMBL1271259
Type:
Small organic molecule
Emp. Form.:
C34H48O5
Mol. Mass.:
536.7419
SMILES:
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(O)C23CC4CC(CC(C4)C2)C3)c(C)c1 |r,THB:24:26:29:33.32.31,34:26:29:33.32.31,34:32:26.27.35:29,31:30:27:33.32.34,31:32:27:35.29.30|
Structure:
Search PDB for entries with ligand similarity: